Korsnes Biocomputing (KoBio)

KoBio is a startup participating in experimental work on computational methods in biology.

We can make visualization products and statistics from your time-lapse recordings of cells grown as monolayers in test wells. This includes the ability via an Internet browser (Firefox or similar) to view and search for cells in different ways. You can follow cells throughout their life spans, browse events of cell division and death, find cells in the video by clicking on their pedigree tree, locate "relative" cells and more.

Here is an illustration (screenshot) from the use of Kobio_Celltrack showing "relative" cells (click to enlarge):

The system is under active development based on Ada 2012 using GLOBE_3D as an OpenGL language binding.

News :

Example from tracking A549 cells exposed to a toxin during 96 hours using Kobio Celltrack. The video was done using Cytation 5 Cell Imaging Multi-Mode Reader from Biotek:

If you have questions about this software,
contact the main developer Reinert Korsnes: email

Video clip showing vacuoles passing from mother cell to her daughters through cell division:

These cells are A549 lung cancer cells exposed to 1000 nM yessotoxin. We prepared this video when tracking the cells for the work "Single-Cell Tracking of A549 Lung Cancer Cells Exposed to a Marine Toxin Reveals Correlations in Pedigree Tree Profiles" . We used 96-multiwell black microplates # 655090 from Greiner Bio-One IT to plate the A549 cells for recording with Cytation 5.

Other cell tracking software:

Related papers:

KORSNES, Mónica Suárez; KORSNES, Reinert. Single-cell tracking of A549 lung cancer cells exposed to a marine toxin reveals correlations in pedigree tree profiles. Frontiers in Oncology, 2018, 8: 260. Full text.

KORSNES, Mónica Suárez; KORSNES, Reinert. Mitotic catastrophe in BC3H1 cells following yessotoxin exposure. Frontiers in Cell and Developmental Biology, 2017, 5. Full text.

KORSNES, Mónica Suárez; KORSNES, Reinert. Lifetime distributions from tracking individual BC3H1 cells subjected to yessotoxin. Frontiers in bioengineering and biotechnology, 2015, 3. Full text.

KORSNES, Reinert, et al. Computer-assisted image processing to detect spores from the fungus Pandora neoaphidis. MethodsX, 2016, 3: 231-241. Full text.

The Nerdy Corner (unrelated):

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